FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\beat-IcUAS.cPa
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General Information
Symbol
Dmel\beat-IcUAS.cPa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Pipes
FlyBase ID
FBal0130495
Feature type
allele
Associated gene
Dmel\beat-Ic
Associated Insertion(s)
Carried in Construct
P{UAS-beat-Ic.P}
Key Links
Transgenic product class
wild_type
(Pipes et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Pipes et al., 2001)
Mutagen
in vitro construct
(Pipes et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-beat-Ic.P}
Cytology
Description

UASt regulatory sequences drive expression of beat-Ic.

(Pipes et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
beat-Ic
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of two copies of beat-IcScer\UAS.cPa under the control of two copies of Scer\GAL4elav.PLu results in defects in ISNb development. Many of the defective ISNb axons tangle and stall as they enter their target muscle field. The RP3 motorneuron stalls in 23% of cases, whereas the RP1 motorneuron only stalls in 5% of cases. The phenotype is dose sensitive. Increased stalling and ectopic exploration of the ventral muscle surfaces by the transverse nerve is also seen in these embryos.

      (Pipes et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      beat-IcUAS.cPa/Scer\GAL4elav.PLu partially rescues Df(2L)TE35D-19/beat-IcRM5

      (Pipes et al., 2001)
      Comments

      Partially rescues the fasciculation defects in the transverse nerve that are seen in beat-IcRM5/Df(2L)TE35D-19 embryos.

      (Pipes et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      beat-IcScer\UAS.cPa
      beat-IcUAS.cPa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Pipes
      (Pipes et al., 2001)
      Secondary FlyBase IDs
        References (1)