FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\FemcoatRNAi.hs.cKa
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General Information
Symbol
Dmel\FemcoatRNAi.hs.cKa
Species
D. melanogaster
Name
FlyBase ID
FBal0131042
Feature type
allele
Associated gene
Dmel\Femcoat
Associated Insertion(s)
Carried in Construct
P{hs-Femcoat.RNAi.K}
Key Links
Transgenic product class
RNAi_reagent
(Kim et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Kim et al., 2002)
Mutagen
in vitro construct
(Kim et al., 2002)
Progenitor genotype
Carried in construct
P{hs-Femcoat.RNAi.K}
Cytology
Description

Template corresponds to nucleotides 171-531 and 171-732 of the Femcoat coding region in reverse orientations, producing a double stranded hairpin RNA. Driven by Hsp70.

(Kim et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Femcoat
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When induced by heatshock in egg chambers, a distinct defect is seen in endochorion formation. Although a small portion of membrane appears to have a wild-type structure, most regions of the membrane show severe abnormalities in chorion formation. In particular pillas are incomplete and appear very sparsely. In addition to defects in the endochorion formation, exochorion fibril structure is often missing. Vitelline membrane formation is not affected.

      (Kim et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      dsRNA is expressed in vivo to study the phenotypic consequences of dsRNA interference (RNAi) of the Femcoat gene.

      (Kim et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      FemcoatRNAi.hs.cKa
      FemcoatdsRNA.hs.cKa
      Name Synonyms
      Secondary FlyBase IDs
        References (2)