FB2026_02 , released June 18, 2026
Allele: Dmel\upd1hs.PM
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General Information
Symbol
Dmel\upd1hs.PM
Species
D. melanogaster
Name
heat shock construct of McGregor
FlyBase ID
FBal0135656
Feature type
allele
Associated gene
Dmel\upd1
Associated Insertion(s)
Carried in Construct
P{hs-upd1.M}
Also Known As
hs-upd
Key Links
Transgenic product class
wild_type
(McGregor et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(McGregor et al., 2002)
Mutagen
in vitro construct
(McGregor et al., 2002)
Progenitor genotype
Carried in construct
P{hs-upd1.M}
Cytology
Description

A heat shock promoter drives expression of upd1.

(McGregor et al., 2002)
Allele components
Component
Use(s)
Encoded product / tool
upd1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of upd1hs.PM in adult females using heat shock results in frequent loss of polar follicle cells from one pole of developing egg chambers. The number of stalk follicle cells is increased, resulting in expanded and morphologically abnormal stalks that can have two or more layers of cells. The cells do not have the flattened, disc-shaped morphology of mature stalk cells. The expansion in number of stalk cells does not appear to be due to increased proliferation of the precursors. Some egg chambers fusions are also seen. Condensed chromatin morphology characteristic of stage 4 cysts is seen in many much older egg chambers and the oocyte is sometimes misplaced.

      (McGregor et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      oshs.PM
      upd1hs.PM
      Name Synonyms
      heat shock construct of McGregor
      (McGregor et al., 2002)
      Secondary FlyBase IDs
        References (2)