FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rac1F37A.UAS.Tag:MYC
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General Information
Symbol
Dmel\Rac1F37A.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0135837
Feature type
allele
Associated gene
Dmel\Rac1
Associated Insertion(s)
Carried in Construct
P{UAS-Myc-Rac1.F37A}
Key Links
Transgenic product class
missense_variant
(Ng et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Ng et al., 2002)
Mutagen
in vitro construct
(Ng et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-Myc-Rac1.F37A}
Cytology
Description

UASt regulatory sequences drive expression of a mutated form of Rac1 (carries the amino acid replacement F37A) tagged at the N-terminal end with two copies of Tag:MYC.

(Ng et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Rac1
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Rac1F37A.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4OK107 does not disrupt mushroom body axon patterning in a wild-type background.

      (Ng et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Mushroom body axon growth defects in single-cell Rac1J11 Rac2Δ MtlΔ γ neuron clones are not rescued by expression of Rac1F37A.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4OK107.

      (Ng et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rac1F37A.Scer\UAS.T:Hsap\MYC
      Rac1F37A.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)