FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cse1+tTa
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General Information
Symbol
Dmel\Cse1+tTa
Species
D. melanogaster
Name
FlyBase ID
FBal0136108
Feature type
allele
Associated gene
Dmel\Cse1
Associated Insertion(s)
Carried in Construct
P{Cse1.genomic}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Tekotte et al., 2002)
wild_type
(Tekotte et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Tekotte et al., 2002)
wild_type
(Tekotte et al., 2002)
Mutagen
in vitro construct
(Tekotte et al., 2002)
Progenitor genotype
Carried in construct
P{Cse1.genomic}
Cytology
Description

A genomic fragment contains the whole of the Cse1 gene, and the second intron of the mdy gene.

(Tekotte et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Cse1
Encoded product / tool
Cse1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
2L:16,820,926..16,828,127 [-]
Linked to:
EcoRI-NcoI restriction fragment
Comment:

The EcoRI-NcoI fragment rescues the lethality caused by the P{lacW}Cask03902 insertion; position of restriction fragment on reference sequence inferred by FlyBase curator.

(Tekotte et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Cse1+tTa rescues Cse1ts1

      (Tekotte et al., 2002)

      Cse1+tTa rescues Cse1ts28

      (Tekotte et al., 2002)

      Cse1+tTa rescues Cse1k03902

      (Tekotte et al., 2002)
      Comments

      The lethality caused by the P{lacW}Cask03902 insertion is due to its effect on Cas and not mdy; the lethality is rescued by Cas+tTa, which contains the entire Cas gene but lacks the mdy transcription start site and sequences encoding the N-terminal half of the mdy protein.

      (Tekotte et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cas+tTa
      Cse1+tTa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)