FlyBase Allele Report: Dmel\dx[ΔNBS.UAS]

General Information

Symbol

Dmel\dx^ΔNBS.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0138242

Feature type

allele

Associated gene

Dmel\dx

Associated Insertion(s)

Carried in Construct

P{UAS-dx.ΔNBS}

Key Links

Transgenic product class

inframe_deletion

(Matsuno et al., 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Matsuno et al., 2002)

Mutagen

in vitro construct

(Matsuno et al., 2002)

Progenitor genotype

Carried in construct

P{UAS-dx.ΔNBS}

Cytology

Description

UASt sequences drive expression of dx which has had amino acids 46 to 204, a N binding domain, removed.

(Matsuno et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^ap-md544

(Capilla et al., 2012)

Phenotype Manifest In

leg, with Scer\GAL4^ap-md544

(Capilla et al., 2012)

leg joint, with Scer\GAL4^ap-md544

(Capilla et al., 2012)

Detailed Description

Statement

Reference

Expression of dx^{ΔNBS.Scer\UAS} under the control of Scer\GAL4^ap-md544 partially inhibits normal joint formation in the leg.

(Capilla et al., 2012)

When dx^{ΔNBS.Scer\UAS} is driven by Scer\GAL4^ptc-559.1 very little effect is seen on the wing. No extra sensory organ precursors are seen in the wing disc.

(Matsuno et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^ap-md544/dx^ΔNBS.UAS is a suppressor of visible phenotype of dsh¹

(Capilla et al., 2012)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^ap-md544/dx^ΔNBS.UAS is a suppressor of leg joint | ectopic phenotype of dsh¹

(Capilla et al., 2012)

Scer\GAL4^ap-md544/dx^ΔNBS.UAS is a suppressor of leg phenotype of dsh¹

(Capilla et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of dx^{ΔNBS.Scer\UAS} under the control of Scer\GAL4^ap-md544 in a dsh¹ background partially inhibits normal joint formation in the leg (this phenotype seen in dx^{ΔNBS.Scer\UAS}, Scer\GAL4^ap-md544 single mutant) and partially suppresses the formation of ectopic leg joints seen in dsh¹ single mutants.

(Capilla et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Dx^ΔNBS

(Matsuno et al., 2002)

dx^{ΔNBS.Scer\UAS}

dx^ΔNBS.UAS

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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