FB2026_02 , released June 18, 2026
Allele: Dmel\Sod2Act5C.PS
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General Information
Symbol
Dmel\Sod2Act5C.PS
Species
D. melanogaster
Name
Actin 5C promoter construct of Su
FlyBase ID
FBal0138382
Feature type
allele
Associated gene
Dmel\Sod2
Associated Insertion(s)
Carried in Construct
P{Act5C(-FRT)Sod2.S}
Key Links
Transgenic product class
cDNA
(Sun et al., 2002)
wild_type
(Sun et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Sun et al., 2002)
wild_type
(Sun et al., 2002)
Mutagen
FLPase
(Sun et al., 2002)
Progenitor genotype
Sod2FRT.Act5C
(Sun et al., 2002)
Carried in construct
P{Act5C(-FRT)Sod2.S}
Cytology
Description

The FRT cassette has been excised, juxtaposing Act5C promoter with Sod2 coding sequences.

(Sun et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Act5C
Encoded product / tool
Sod2
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mean life span is increased in by an average of 16% in flies expressing Sod2Act5C.PS, with increases of 30-33% being seen in some lines. Maximum life span is increased by an average of 15%, with one line showing a 37% increase.

      (Sun et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Sod2Act5C.PS and CatAct5C.PS has neutral or negative effects on life span.

      (Sun et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Sod2Act5C.PS
      Name Synonyms
      Actin 5C promoter construct of Su
      (Sun et al., 2002)
      Secondary FlyBase IDs
        References (1)