FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pygoF66
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General Information
Symbol
Dmel\pygoF66
Species
D. melanogaster
Name
FlyBase ID
FBal0140972
Feature type
allele
Associated gene
Dmel\pygo
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Belenkaya et al., 2002)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q69term.

(Belenkaya et al., 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:31,579,426..31,579,426 [-]
Nucleotide change:

C31579426T

Amino acid change:

Q69term | pygo-PA

Reported amino acid change:

Q69term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Belenkaya et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous clones in the wing cause notching of the wing with ectopic wing margin bristles in nearby wild-type tissue. This phenotype is fully penetrant. Homozygous embryos dervied from homozygous female germline clones die with a strong segment polarity phenotype; the embryos have a "lawn of denticles" phenotype and fail to secrete naked cuticle. Zygotically wild-type embryos dervied from homozygous female germline clones develop a pair-rule phenotype with denticle deletions.

      (Belenkaya et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      pygoEP1076

      (Belenkaya et al., 2002)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pygoF66
      (Jordan et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)