FB2026_03 , released September 17, 2026
Allele: Dmel\oskM1R
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General Information
Symbol
Dmel\oskM1R
Species
D. melanogaster
Name
FlyBase ID
FBal0141007
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
oskM1R
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

Construct: Nucleotide substitution: A?C. Nucleotide substitution: T?G. Nucleotide substitution: G?C. Amino acid replacement: M1R. Transgene encoding osk with a mutation in the first start codon. Only the short osk protein isoform is produced by this construct.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

71-78% of embryos expressing oskM1R in a oskA87/Df(3R)p-XT103 background hatch. The unhatched embryos develop cuticles with patterning defects; 50% have posterior defects, 25-30% have anterior defects and 20-25% have both posterior and anterior defects. 49-54% of females derived from the embryos that hatch have wild-type ovaries, while 40-51% have rudimentary ovaries. 84-91% of embryos expressing both oskM1R and oskM139L in a oskA87/Df(3R)p-XT103 background hatch. The unhatched embryos develop cuticles without obvious patterning defects. 100% of females derived from the embryos that hatch have wild-type ovaries.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)