FB2026_02 , released June 18, 2026
Allele: Dmel\SLC5A11UY1824
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General Information
Symbol
Dmel\SLC5A11UY1824
Species
D. melanogaster
Name
FlyBase ID
FBal0141868
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

P{Mae-UAS.6.11} insertion 374bp upstream of the transcription start site of CG8451, such that overexpression from the P{Mae-UAS.6.11} insertion results in overexpression of CG8451.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

SLC5A11EY21708/SLC5A11UY1824 flies show defects in taste-independent nutrient selection. When L-glucose is more concentrated, the flies choose L-glucose over D-glucose in a two-choice assay after 18 hours of starvation.

Expression of SLC5A11UY1824 under the control of Scer\GAL4da.G32 results in a shorter life span under control conditions and in an increased resistance to hydrogen peroxide, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
CG8451UY1824
SLC5A11UY1824
Name Synonyms
Secondary FlyBase IDs
    References (2)