FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sroO4-105
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General Information
Symbol
Dmel\sroO4-105
Species
D. melanogaster
Name
FlyBase ID
FBal0144218
Feature type
allele
Associated gene
Dmel\sro
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Giesen et al., 2003)
Progenitor genotype
Cytology
Description

Nucleotide substitution: C?T.

(Niwa et al., 2010)

Amino acid replacement: Q162term.

(Niwa et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:29,795,174..29,795,174 [+]
Nucleotide change:

C29795174T

Reported nucleotide change:

C?T

Amino acid change:

Q162term | sro-PA

Reported amino acid change:

Q162term

(Niwa et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      sro1/sroO4-105 animals normally die as embryos, but if they are treated with 20-hydroxyecdysone midway through embryogenesis, approximately 52% hatch into first instar larvae. Approximately 45% of these rescued animals grow into second instar larvae if they are raised on a diet supplemented with 20-hydroxyecdysone.

      (Niwa et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      sroO4-105 complements kay1.

      (Niwa et al., 2010)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      kayO4-105
      sroO4-105
      (Niwa et al., 2010, Giesen et al., 2003)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)