No mutation has been found within the exons or introns of the transcription unit.
hydK3.5 clones die 2-3 days post generation in larval wing imaginal discs and are removed from the epithelium.
Homozygous clones in the eye disc induce outgrowths of the wild-type tissue surrounding the clone, although the clones themselves so not persist to adulthood. The clones either form scars in the adult eye or head cuticle at its margin. Premature photoreceptor differentiation is seen in clones in a region just anterior to the morphogenetic furrow, with the ectopic differentiation spreading beyond the borders of the mutant clone into the surrounding wild-type tissue. Rarely, photoreceptor differentiation is seen in clones lying near the anterior margin. Mutant clones in the posterior of the eye disc are generally smaller than similar wild-type clones and contain reduced numbers of photoreceptors. Mutant clones in the eye induced in a Minute background result in pharate adults with greatly reduced eyes. The eyes do appear to contain properly formed hydK3.5 mutant ommatidia.
hydK3.5 has photoreceptor neuron | ectopic | somatic clone phenotype, suppressible by hhrJ413
hydK3.5 has eye disc | somatic clone | cell non-autonomous phenotype, suppressible by hhrJ413