FlyBase Allele Report: Dmel\aop[MutNLS.UAS]

General Information

Symbol

Dmel\aop^MutNLS.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0144453

Feature type

allele

Associated gene

Dmel\aop

Associated Insertion(s)

Carried in Construct

P{UAS-yan.MutNLS}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Tootle et al., 2003)

Progenitor genotype

Carried in construct

P{UAS-yan.MutNLS}

Cytology

Description

UASt regulatory sequences drive expression of aop with a non-functional nuclear localisation signal inserted into the middle of the aop protein.

(Tootle et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

aop

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Embryos expressing aop^{MutNLS.Scer\UAS.T:SV40\nls2-Mut} under the control of Scer\GAL4^elav-C155 wild-type neuronal differentiation in the central nervous system.

(Tootle et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Carried in a plasmid, transfected into S2 cells and used to study the nuclear export of aop protein.

(Tootle et al., 2003)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

YAN^MutNLS

(Tootle et al., 2003)

aop^{MutNLS.Scer\UAS.T:SV40\nls-largeT-Mut}

aop^{MutNLS.Scer\UAS.T:SV40\nls2-Mut}

aop^{MutNLS.Scer\UAS}

aop^MutNLS.UAS

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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