FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Or47aUAS.cDa
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General Information
Symbol
Dmel\Or47aUAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Dobritsa
FlyBase ID
FBal0152323
Feature type
allele
Associated gene
Dmel\Or47a
Associated Insertion(s)
Carried in Construct
P{UAS-Or47a.D}
Key Links
Transgenic product class
genomic_DNA
(Dobritsa et al., 2003)
wild_type
(Dobritsa et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Dobritsa et al., 2003)
wild_type
(Dobritsa et al., 2003)
Mutagen
in vitro construct
(Dobritsa et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-Or47a.D}
Cytology
Description

UASt regulatory sequences drive expression of a genomic fragment extending from immediately 5' to the Or47a translation initiation codon to immediately 3' of the stop codon.

(Dobritsa et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Or47a
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      large sensillum basiconicum of antennal segment 3 & olfactory neuron, with Scer\GAL4Or22a.8197

      (Dobritsa et al., 2003)
      Detailed Description
      Statement
      Reference

      The ab3A neurons in the antenna of flies expressing Or47aScer\UAS.cDa under the control of Scer\GAL4Or22a.8197 in a wild-type background have a dose-response curve for ethyl butyrate that is identical to that of wild-type ab3A neurons. The response to pentyl acetate in the mutant ab3A neurons is greater than that of wild-type ab3A neurons.

      (Dobritsa et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      Dp(2;2)dppd21/Df(2L)dp-79b, Or47aUAS.cDa, Scer\GAL4Or22a.8197 has large sensillum basiconicum of antennal segment 3 & olfactory neuron phenotype

      (Dobritsa et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When Or47aScer\UAS.cDa is expressed under the control of Scer\GAL4Or22a.8197 in a "Δhalo" background (in which Df(2L)dp-79b and Dp(2;2)dppd21 are recombined onto the same chromosome to create a synthetic deficiency), the olfactory receptor neurons which neighbour an ab3B cell in large basiconic sensilla of the antenna have a response pattern to odours which is similar to that of an ab5B neuron (these cells normally have the characteristic of an ab3A neuron). These neurons still target the DM2 glomerulus (the wild-type target for ab3A neurons).

      (Dobritsa et al., 2003)

      When Or47aScer\UAS.cDa is expressed under the control of Scer\GAL4Or22a.8197 in a Df(2L)dp-79b/Dp(2;2)dppd21 background, the olfactory receptor neurons which neighbour an ab3B cell in large basiconic sensilla of the antenna have a response pattern to odours which is similar to that of an ab5B neuron (these cells normally have the characteristic of an ab3A neuron). These neurons still target the DM2 glomerulus (the wild-type target for ab3A neurons).

      (Dobritsa et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Or47aScer\UAS.cDa
      Or47aUAS.cDa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Dobritsa
      (Dobritsa et al., 2003)
      Secondary FlyBase IDs
        References (3)