FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mkp35
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General Information
Symbol
Dmel\Mkp35
Species
D. melanogaster
Name
FlyBase ID
FBal0152422
Feature type
allele
Associated gene
Dmel\Mkp3
Associated Insertion(s)
P{EP}11
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Rintelen et al., 2003)
Progenitor genotype
P{EP}11
(Rintelen et al., 2003)
Associated Insertion(s)
P{EP}11
Cytology
Description

G to A nucleotide substitution affects a splice-acceptor site resulting in a frameshift by one base in the mRNA. The progenitor P{EP}Mkp311 insertion is still present on the chromosome.

(Rintelen et al., 2003)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:19,069,890..19,069,890 [-]
Nucleotide change:

G19069890A

Comment:

The mutation occurs in a splice acceptor site and leads to a 1 bp frameshift in the CDS as confirmed by sequence analysis of cDNA.

(Rintelen et al., 2003)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a revertant of the phenotype caused by overexpression from the P{EP}Mkp311 insertion.

      (Rintelen et al., 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dmkp35
      (Rintelen et al., 2003)
      Mkp35
      Name Synonyms
      Secondary FlyBase IDs
        References (1)