FB2026_02 , released June 18, 2026
Allele: Dmel\Abd-BFab7-2.scs-prom
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General Information
Symbol
Dmel\Abd-BFab7-2.scs-prom
Species
D. melanogaster
Name
FlyBase ID
FBal0152807
Feature type
allele
Associated gene
Dmel\Abd-B
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

gain of function allele

Mutagen
Nature of the Allele
Allele class

gain of function allele

(Hogga and Karch, 2002)
Mutagen
gene conversion
(Hogga and Karch, 2002)
Progenitor genotype
Abd-BFab7-2.tHa.scs-prom
(Hogga and Karch, 2002)
Cytology
Description

Gene conversion using Abd-BFab7-2.tHa.scs-prom as a donor template, which results in the endogenous Fab-7 sequences being replaced with those in Abd-BFab7-2.tHa.scs-prom (producing a chromosome with the Fab-72 deletion with scsprom inserted upstream of it, with the scsprom fragment oriented such that the PstI end is next to the Fab-72 deletion endpoint).

(Hogga and Karch, 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In homozygous males, segment A6 is completely transformed into A7, as revealed by the complete absence of tergite or sternite tissue in the position of A6 in adults. Heterozygotes have the same phenotype, although not as severe. Homozygous females show transformation of A7 into A8, as shown by a strong reduction of the seventh tergite in adults. In addition, the sixth tergite is also reduced in size.

      (Hogga and Karch, 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Abd-BFab7-2.scs-prom
      Name Synonyms
      Secondary FlyBase IDs
        References (1)