FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rnoUAS.Tag:MYC
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General Information
Symbol
Dmel\rnoUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0154689
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

UASt sequences drive expression of the full length rno cDNA in which the Tag:MYC epitope tag is inserted, fused in frame to the second codon of the rno ORF.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The eye discs of rnoScer\UAS.T:Hsap\MYC; Scer\GAL4GMR.PF larvae and pupae have normal numbers of photoreceptors and cone cells per ommatidium, and only a small increase in pigment cells (average 2.1 per ommatidium, compared to 2.0 in wild-type). The most severe defect is an absence of interommatidial bristles at mid-pupal stages. In contrast, adults of this genotype have a very severe eye phenotype, completely lacking rhabdomeres or a hexagonal pigment cell lattice. The retina is instead populated with vacuoles and scattered pigment granules. The eye discs of rnoScer\UAS.T:Hsap\MYC; Scer\GAL4hs.2sev larvae and pupae appear normal, but adult eyes have a degenerated interommatidial lattice.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
rnoScer\UAS.T:Hsap\MYC
rnoUAS.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (1)