FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nabUAS.cCa
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General Information
Symbol
Dmel\nabUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Clements
FlyBase ID
FBal0154841
Feature type
allele
Associated gene
Dmel\nab
Associated Insertion(s)
Carried in Construct
P{UAS-nab.C}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Clements et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-nab.C}
Cytology
Description

UASt regulatory sequences drive expression of nab cDNA sequences (nucleotides 169-1657) followed by a stop codon.

(Clements et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
nab
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Animals expressing nabScer\UAS.cCa under the control of Scer\GAL4ey.PH usually completely lack eyes; occasionally a tiny patch of eye tissue can be seen. Animals containing a more weakly expressed nabScer\UAS.cCa transgene (expressed under the control of Scer\GAL4ey.PH) have extremely small eyes containing a few ommatidia. Animals expressing nabScer\UAS.cCa under the control of Scer\GAL4GMR.PF have glassy eyes with fused facets and an irregular surface. Loss of eye pigmentation is also seen. Animals expressing nabScer\UAS.cCa under the control of Scer\GAL4hs.2sev have a rough eye phenotype with many dark necrotic patches.

      (Clements et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of sqzScer\UAS.cAa and nabScer\UAS.cCa under the control of Scer\GAL4elav-C155 results in a significant increase in the number of SELK neurons.

      (Losada-Pérez et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      nabScer\UAS.cCa
      nabUAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Clements
      (Clements et al., 2003)
      Secondary FlyBase IDs
        References (2)