FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mei(2)yoh71341
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General Information
Symbol
Dmel\mei(2)yoh71341
Species
D. melanogaster
Name
FlyBase ID
FBal0154960
Feature type
allele
Associated gene
mei(2)yoh7134
Associated Insertion(s)
P{}mei(2)yoh71341
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{}mei(2)yoh71341
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        C(1;Y)6/Dp(1;f)YP223 males that are homozygous for mei(2)yoh71341 show an increased frequency of non-disjunction of the sex chromosomes (6.2%) and fourth chromosomes (8.7%) compared to wild type. Homozygous XY males show an increased frequency of non-disjunction of the sex chromosomes (2.8%) and fourth chromosomes (6.9%) compared to wild type (0.1 and 0.3% respectively). Analysis of the progeny of homozygous males mated to compound-X females indicates that mei(2)yoh71341 exclusively affects meiosis I. Homozygous female lay a large number of eggs with normal eggshell morphology, but nuclear divisions become abnormal by the syncytial blastoderm stage.

        (Hirai et al., 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Excision of the P-element can revert both the male meiotic and female sterile mutant phenotypes.

        (Hirai et al., 2004)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        mei(2)yoh7134
        (Hirai et al., 2004)
        mei(2)yoh71341
        Name Synonyms
        Secondary FlyBase IDs
          References (1)