FB2026_03 , released September 17, 2026
Allele: Dmel\mei(2)yh1491
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General Information
Symbol
Dmel\mei(2)yh1491
Species
D. melanogaster
Name
FlyBase ID
FBal0154963
Feature type
allele
Associated gene
mei(2)yh149
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hirai et al., 2004)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      C(1;Y)6/Dp(1;f)YP223 males that are homozygous for mei(2)yh1491 show a slightly increased frequency of non-disjunction of the sex chromosomes (2.3%) and fourth chromosomes (2.4%) compared to wild type (0.8 and 0.1% respectively). Homozygous XY males show a slightly increased frequency of non-disjunction of the sex chromosomes (1.2%) and fourth chromosomes (1.0%) compared to wild type (0.1 and 0.3% respectively). Analysis of the progeny of homozygous males mated to compound-X females indicates that mei(2)yh1491 induces either nondisjunction at meiosis II or chromosome loss at meiosis I and/or II. Nondisjunction frequencies of the X and fourth chromosomes in homozygous females are comparable to those of controls.

      (Hirai et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mei(2)yh149
      (Hirai et al., 2004)
      mei(2)yh1491
      Name Synonyms
      Secondary FlyBase IDs
        References (1)