FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kek1176V.UAS.GFP
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General Information
Symbol
Dmel\kek1176V.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0155168
Feature type
allele
Associated gene
Dmel\kek1
Associated Insertion(s)
Carried in Construct
P{UAS-kek1.176V.GFP}
Key Links
Transgenic product class
missense_variant
(Alvarado et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Alvarado et al., 2004)
Mutagen
ethyl methanesulfonate
(Alvarado et al., 2004)
in vitro construct
(Alvarado et al., 2004)
Progenitor genotype
kek1UAS.GFP
(Alvarado et al., 2004)
Carried in construct
P{UAS-kek1.176V.GFP}
Cytology
Description

Construct: Amino acid replacement: P356S.

(Alvarado et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
kek1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When driven by Scer\GAL4GMR.PF gives a weaker eye phenotype than kek1Scer\UAS.T:Avic\GFP driven by Scer\GAL4GMR.PF. When driven by Scer\GAL4CY2 gives a weaker chorion phenotype than kek1Scer\UAS.T:Avic\GFP driven by Scer\GAL4CY2.

      (Alvarado et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Isolated in a mutagenic screen to find suppressor of the kek1Scer\UAS.T:Avic\GFP (Scer\GAL4GMR.PF) eye phenotype.

      (Alvarado et al., 2004)
      Comments
      Comments

      Carried in a plasmid and transfected into S3 cells for C-immunoprecipitation experiments.

      (Alvarado et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      kek1176V.Scer\UAS.T:Avic\GFP
      kek1176V.UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)