FlyBase Allele Report: Dmel\UY2635[UY2635]

General Information

Symbol

Dmel\UY2635^UY2635

Species

D. melanogaster

Name

FlyBase ID

FBal0155726

Feature type

allele

Associated gene

UY2635

Associated Insertion(s)

P{Mae-UAS.6.11}UY2635^UY2635

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Nicolai et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{Mae-UAS.6.11}UY2635^UY2635

Cytology

Description

Insertion site maps to -5kb of the known/supposed transcription start site of plexA.

(Nicolai et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{Mae-UAS.6.11}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^7B

(Nicolai et al., 2003)

abnormal neuroanatomy, with Scer\GAL4^c739

(Nicolai et al., 2003)

viable, with Scer\GAL4^7B

(Nicolai et al., 2003)

viable, with Scer\GAL4^c739

(Nicolai et al., 2003)

Phenotype Manifest In

adult mushroom body beta-lobe, with Scer\GAL4^c739

(Nicolai et al., 2003)

Kenyon cell, with Scer\GAL4^7B

(Nicolai et al., 2003)

Kenyon cell, with Scer\GAL4^c739

(Nicolai et al., 2003)

mushroom body & axon, with Scer\GAL4^7B

(Nicolai et al., 2003)

mushroom body & axon, with Scer\GAL4^c739

(Nicolai et al., 2003)

Detailed Description

Statement

Reference

When expression is driven by Scer\GAL4^7B or Scer\GAL4^c739, UY2635^UY2635 shows a mushroom body Class III phenotype; axonal growth and guidance defects. The beta lobe axons do not stop at the interhemispheric boundary. The phenotype is more striking with Scer\GAL4^c739 than with Scer\GAL4^7B or Scer\GAL4^OK107.

(Nicolai et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

7353

y¹ w^67c23; P{Mae-UAS.6.11}UY2635^UY2635

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

UY2635^UY2635

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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