FB2026_02 , released June 18, 2026
Allele: Dmel\Top1Wee-P153
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General Information
Symbol
Dmel\Top1Wee-P153
Species
D. melanogaster
Name
FlyBase ID
FBal0155750
Feature type
allele
Associated gene
Dmel\Top1
Associated Insertion(s)
P{Wee-P.ph0}Top1Wee-P153
Carried in Construct
Also Known As
Wee-P153
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{Wee-P.ph0}Top1Wee-P153
    Cytology
    Description

    Insertion of a P{Wee-P.ph0} element into Top1, resulting in the expression of a Top1 fusion protein which is tagged with T:Avic\GFP. The GFP fusion event is predicted to be an internal fusion.

    (Clyne et al., 2003)
    Allele components
    Component
    Use(s)
    Inserted element
    P{Wee-P.ph0}
    Tagged with
    EGFP
    Also carries
    FRT
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Salivary gland nuclei are larger in size than normal in larvae expressing Top1Wee-P153 under the control of Scer\GAL4Sgs3.PD.

        (Juge et al., 2010)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Top1Wee-P153
        Name Synonyms
        Secondary FlyBase IDs
          References (2)