FlyBase Allele Report: Dmel\Tep4[EY04656]

General Information

Symbol

Dmel\Tep4^EY04656

Species

D. melanogaster

Name

FlyBase ID

FBal0155764

Feature type

allele

Associated gene

Dmel\Tep4

Associated Insertion(s)

P{EPgy2}Tep4^EY04656

Carried in Construct

Also Known As

EY04656

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}Tep4^EY04656

Cytology

Description

Insertion in the initiation codon of Tep4.

(Bou Aoun et al., 2011)

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:19,549,893..19,549,893 [-]

(Vincow et al., 2024, Caravello et al., 2022, Harbison et al., 2019, Dostálová et al., 2017, Bou Aoun et al., 2011, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal immune response

(Cai et al., 2026)

increased mortality

(Cai et al., 2026)

Phenotype Manifest In

Detailed Description

Statement

Reference

Mutant flies are not more susceptible to infection with either E. faecalis, M. marinum, L. monocytogenes, S.aureus, E. cloacae or S. pyogenes (via septic injury) than wild-type controls.

(Bou Aoun et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Df(2L)Tep2-Tep3, Tep4^EY04656 has abnormal immune response phenotype

(Cai et al., 2026)

Df(2L)Tep2-Tep3, Tep4^EY04656 has increased mortality phenotype

(Cai et al., 2026)

Df(2L)Tep2-Tep3, Tep1^MI04262, Tep4^EY04656 has abnormal immune response phenotype

(Cai et al., 2026)

Df(2L)Tep2-Tep3, Tep1^MI04262, Tep4^EY04656 has increased mortality phenotype

(Cai et al., 2026)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

15936

y¹ w^67c23; P{EPgy2}Tep4^EY04656

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

EY04656

(Haller et al., 2018)

Tep4 (EY04656)

(Cai et al., 2026)

Tep4^EY04656

Tep4^Δ

(Cai et al., 2026)

TepIV^EY04656

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

Open Close