FB2026_02 , released June 18, 2026
Allele: Dmel\NRam*Δ3.UAS
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General Information
Symbol
Dmel\NRam*Δ3.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0156164
Feature type
allele
Associated gene
Dmel\N
Associated Insertion(s)
Carried in Construct
P{UAS-N.Ram*Δ3}
Key Links
Transgenic product class
inframe_deletion
(Le Gall and Giniger, 2004)
missense_variant
(Le Gall and Giniger, 2004)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Le Gall and Giniger, 2004)
missense_variant
(Le Gall and Giniger, 2004)
Mutagen
in vitro construct
(Le Gall and Giniger, 2004)
Progenitor genotype
NΔ3.UAS
(Le Gall and Giniger, 2004)
Carried in construct
P{UAS-N.Ram*Δ3}
Cytology
Description

Triple point mutation in the RAM domain (amino acid replacements W1776L, F1777L and P1778A), which mutates the Su(H) protein binding sites.

(Le Gall and Giniger, 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
N
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Expression of NRam*Δ3.Scer\UAS under the control of Scer\GAL4sca-537.4 only results in very weak rescue of the severe hyperplasia of the central and peripheral nervous systems seen in N55e11 mutant embryos.

      (Le Gall and Giniger, 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells to study protein-protein interactions between Su(H) and N.

      (Le Gall and Giniger, 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      NRam*Δ3.Scer\UAS
      NRam*Δ3.UAS
      NFL Ram* Δ3
      (Le Gall and Giniger, 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)