FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rcc1VV179
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General Information
Symbol
Dmel\Rcc1VV179
Species
D. melanogaster
Name
FlyBase ID
FBal0157263
Feature type
allele
Associated gene
Dmel\Rcc1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Shi and Skeath, 2004)
Mutagen
ethyl methanesulfonate
(Shi and Skeath, 2004)
Progenitor genotype
Cytology
Description

Nucleotide substitution: C1714T. Amino acid replacement: P?L. The mutation is near the end of the fourth RCC repeat.

(Shi and Skeath, 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:5,931,060..5,931,060 [-]
Nucleotide change:

C5931060T

Reported nucleotide change:

C1714T

Amino acid change:

P388L | Rcc1-PA; P388L | Rcc1-PB; P388L | Rcc1-PC

Reported amino acid change:

P?L

(Shi and Skeath, 2004)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous mutant embryos exhibit an approximately 50% reduction of EL neurons with 3-5 ELs developing per abdominal hemisegment. These mutant embryos also exhibit morphological defects in the lateral CNS as the lateral margin of mutant nerve cords appear rough and scalloped relative to wild-type.

      (Shi and Skeath, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Rcc1EP3630

      (Shi and Skeath, 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Bj1VV179
      Rcc1VV179
      dRCC1VV179
      (Shi and Skeath, 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)