FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Or7aUAS.Tag:MYC
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General Information
Symbol
Dmel\Or7aUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0160092
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-OR7a
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS sequences drive expression of Or7a tagged with Tag:MYC

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing Or7aScer\UAS.T:Hsap\MYC under the control of Scer\GAL4Or22a.8197 in a Df(2L)dp-79b/Dp(2;2)dppd21 background (called Δhalo) show an increased electrophysiological response to either 2-ethylpyrazine or 2-methylpyrazine.

When Or7aScer\UAS.T:Hsap\MYC is driven by Scer\GAL4Or22a.8197 in Df(2L)dp-79b/Dp(2;2)dppd21 (Δhalo) flies, mutant animals exhibit a strong response to exposure to 1-hexanol and E2-hexanal in the ab3A neuron. A strong response is not seen in response to exposure to ethyl acetate, pentyl acetate, ethyl butyrate,methyl salicylate, 1-octen-3-ol, 2,3-butanedione, 2-heptanone or geranyl acetate. When Or7aScer\UAS.T:Hsap\MYC is driven by Scer\GAL4Or22a.8197 in Df(2L)dp-79b/Dp(2;2)dppd21 (Δhalo) flies, the spontaneous firing rate of the ab3A neuron is seen to be similar to the ab4a neuron, the neuron that normally expresses Or7a. When Or7aScer\UAS.T:Hsap\MYC is driven by Scer\GAL4Or83b.7.087 in the maxillary palp, the neurons in the palp acts to E2-hexanal exposure in the way expected of to the ab4a neuron, the neuron that normally expresses Or7a.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Or7aScer\UAS.T:Hsap\MYC
Or7aUAS.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (8)