FB2026_03 , released September 17, 2026
Allele: Dmel\Or59bUAS.Tag:MYC
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General Information
Symbol
Dmel\Or59bUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0160096
Feature type
allele
Associated gene
Dmel\Or59b
Associated Insertion(s)
Carried in Construct
P{UAS-Or59b.MYC}
Key Links
Transgenic product class
wild_type
(Hallem et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hallem et al., 2004)
Mutagen
in vitro construct
(Hallem et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Or59b.MYC}
Cytology
Description

UAS sequences drive expression of Or59b tagged with Tag:MYC

(Hallem et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Or59b
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When Or59bScer\UAS.T:Hsap\MYC is driven by Scer\GAL4Or22a.8197 in Df(2L)dp-79b/Dp(2;2)dppd21 (Δhalo) flies, mutant animals exhibit a strong response to exposure to ethyl acetate or 2,3-butanedione in the ab3A neuron. A strong response is not seen in response to exposure to pentyl acetate, ethyl butyrate, methyl salicylate, 1-hexanol, 1-octen-3-ol, E2-hexanal, 2-heptanone or geranyl acetate. When Or59bScer\UAS.T:Hsap\MYC is driven by Scer\GAL4Or22a.8197 in Df(2L)dp-79b/Dp(2;2)dppd21 (Δhalo) flies, the spontaneous firing rate of the ab3A neuron is seen to be similar to the ab2A neuron, the neuron that normally expresses Or59b. Inhibitory responses for the mutant ab3A neuron appear to be those expected for neurons expressing Or59b.

      (Hallem et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Or59bScer\UAS.T:Hsap\MYC
      Or59bUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)