FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CblEY11427
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General Information
Symbol
Dmel\CblEY11427
Species
D. melanogaster
Name
FlyBase ID
FBal0160714
Feature type
allele
Associated gene
Dmel\Cbl
Associated Insertion(s)
P{EPgy2}CblEY11427
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Yu et al., 2012)
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}CblEY11427
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous CblEY11427 flies show poor survival to adulthood.

      Less than half of CblEY11427/CblKG03080 mutant males survive to adulthood.

      Pupation is delayed by approximately 24 hours in CblEY11427/CblKG03080 larvae compared with wild-type controls.

      CblEY11427/CblKG03080 males show increased sensitivity to starvation, exhibiting an approximately 20% decrease in the median survival time upon food deprivation.

      CblEY11427/CblKG03080 males display a dramatically shortened lifespan, with an approximately 67% reduction in the median lifespan compared with wild-type controls.

      (Yu et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CblEY11427
      dCblEY
      (Yu et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)