FB2026_02 , released June 18, 2026
Allele: Dmel\ninaGP330
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General Information
Symbol
Dmel\ninaGP330
Species
D. melanogaster
Name
FlyBase ID
FBal0175565
Feature type
allele
Associated gene
Dmel\ninaG
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: Q81term.

    (Sarfare et al., 2005)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:11,421,289..11,421,289 [-]
    Nucleotide change:

    C11421289T

    Reported nucleotide change:

    C241T

    Amino acid change:

    Q81term | ninaG-PA; Q81term | ninaG-PB

    Reported amino acid change:

    Q81term

    (Sarfare et al., 2005)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        ninaGP330 animals exhibit defects in the function of abdominal lateral pentascolopidial chordotonal organ lch5 (in third instar larvae) and Johnston organ (in adults) mechanoreceptors compared to controls.

        (Katana et al., 2019)

        Electroretinogram data shows that in ninaGP330 mutant flies, a bright blue light stimulus fails to induce a prolonged depolarising after-potential. The ultrastucture of photoreceptor cells in these mutants is abnormal: R1-6 rhabdomere's are reduced in size and there is an excessive accumulation of rough endoplasmic reticulum compared to wild-type.

        (Sarfare et al., 2005)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        ninaGP330 is rescued by ninaG+t3.8

        (Sarfare et al., 2005)
        Comments

        ninaG+t3.8 rescues the prolonged depolarising after-potential response to bright blue light lost in ninaGP330 mutants.

        (Sarfare et al., 2005)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        ninaGP330
        (Katana et al., 2019, Ahmad et al., 2006, Ahmad et al., 2006, Sarfare et al., 2005)
        Name Synonyms
        Secondary FlyBase IDs
          References (5)