FB2026_02 , released June 18, 2026
Allele: Dmel\uncunspecified
Open Close
General Information
Symbol
Dmel\uncunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0177292
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Early events in spermatogenesis, from meiosis to `onion' stage spermatids, appear normal in uncunspecified mutants. However, in mutant elongating spermatid cysts, nuclei are dispersed along the flagellar bundle and are frequently separated from their centriole adjuncts in mutant elongating spermatid cysts and the number of axoneme profiles in each cyst is reduced by an average of 73% (17/64 intact axonemes, n=5). Some of the remaining axonemes appear unaffected, but many show defects ranging from a single break to complete disruption of the axoneme into its constituent microtubule doublets. In uncunspecified mutants the cilia extending from the sensory processes of antennal olfactory neurons are missing or truncated. The scolopidial cilia of femoral chordotonal organs in these flies are also missing or truncated. Transverse sections of the bases of these cilia show some broken rings in the distal part of the basal body. Proximal basal bodies, ciliary rootlets and non-neuronal sensory structures are not visibly affected. Spermatocyte centrioles in uncunspecified mutants have a similar ultrastructure to wild-type, with with microtubule triplets clearly present, but both the centrioles are shorter.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    uncunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (2)