FlyBase Allele Report: Dmel\simj[L]

General Information

Symbol

Dmel\simj^L

Species

D. melanogaster

Name

FlyBase ID

FBal0177953

Feature type

allele

Associated gene

Dmel\simj

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Kon et al., 2005)

Progenitor genotype

Cytology

Description

Nucleotide substitution: G?A. Mutation in a conserved exon/intron boundary, which is predicted to result in a truncated protein that lacks the last 80 amino acids.

(Kon et al., 2005)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage (with simj¹⁶)

(Kon et al., 2005)

melanotic necrosis | pupal stage (with simj^A)

(Kon et al., 2005)

some die during pupal stage (with simj¹⁶)

(Kon et al., 2005)

Phenotype Manifest In

metathoracic leg | P-stage (with simj¹⁶)

(Kon et al., 2005)

Detailed Description

Statement

Reference

simj^L/simj¹⁶ animals survive to the late pupal stage. The pupae appear almost wild-type, but do display a variety of phenotypes, including short third legs. simj^A/simj^L pupae sometimes show necrosis hear the head region.

(Kon et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

simj^unspecified

(Kon et al., 2005)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Order of alleles (from weak to strong) is: simj¹⁶, simj⁷, simj^L, simj^S, simj^H, simj^J = simj¹⁰ = simj^A = Df(3L)lxd6.

(Kon et al., 2005)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

p66^L

(Kon et al., 2005)

simj^L

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close