FB2026_02 , released June 18, 2026
Allele: Dmel\bi::org-1org-1N+biT+biC.UAS.Tag:HA,Tag:MYC
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General Information
Symbol
Dmel\bi::org-1org-1N+biT+biC.UAS.Tag:HA,Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0180807
Feature type
allele
Associated gene
bi::org-1
Associated Insertion(s)
Carried in Construct
P{UAS-org-1N+biT+biC.MYC}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Porsch et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-org-1N+biT+biC.MYC}
Cytology
Description

The org-1 N, bi T and bi C domains have been fused in order separated by two or three junctional amino acids (A,G or T). Tag:MYC tags are at the C and N termini. A Tag:HA tag has been placed at the N terminus, a Tag:MYC tag at the C terminus. Expression of this construct is driven by UASt sequences.

(Porsch et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
bi::org-1
Tagged with
Tag:HA
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When bi::org-1org-1N+biT+biC.Scer\UAS.T:Ivir\HA1,T:Hsap\MYC is driven by Scer\GAL4dpp.blk1 eye development is suppressed. Animals also lack aristae. When bi::org-1org-1N+biT+biC.Scer\UAS.T:Ivir\HA1,T:Hsap\MYC is driven by Scer\GAL4GMR.PF interommatidial bristle development is impaired, but ommatidia look almost normal.

      (Porsch et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bi::org-1org-1N+biT+biC.Scer\UAS.T:Ivir\HA1,T:Hsap\MYC
      bi::org-1org-1N+biT+biC.UAS.Tag:HA,Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)