FB2026_03 , released September 17, 2026
Allele: Dmel\SppM
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General Information
Symbol
Dmel\SppM
Species
D. melanogaster
Name
FlyBase ID
FBal0181468
Feature type
allele
Associated gene
Dmel\Spp
Associated Insertion(s)
Carried in Construct
P{SppM}
Key Links
Transgenic product class
missense_variant
(Casso et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Casso et al., 2005)
Mutagen
in vitro construct
(Casso et al., 2005)
Progenitor genotype
Spp+t5.3
(Casso et al., 2005)
Carried in construct
P{SppM}
Cytology
Description

Mutation of the two catalytic aspartate residues to alanines.

(Casso et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
Spp
Encoded product / tool
Spp
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      SppM fails to rescue Spp14

      (Casso et al., 2005)
      Comments

      SppM fails to rescue the lethality of Spp14 mutants (Df(2L)lwr14 homozygotes in which the loss of lwr function has been rescued using lwr+t2.4).

      (Casso et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      SppM
      Name Synonyms
      Secondary FlyBase IDs
        References (1)