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General Information
Symbol
Dsim\Hmr+t8.6
Species
D. simulans
Name
FlyBase ID
FBal0184055
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Approximately 8.6kb NotI/XbaI genomic fragment that extends from approximately 2.8kb 5' of Dsim\Hmr to approximately 1.05kb 3' of Dsim\Hmr. This fragment also contains the complete predicted coding region of Dsim\CG2124.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Hmr2 suppresses hybrid male lethality of hybrid sons of crosses between D.melanogaster females and D.simulans males. This hybrid rescue is not suppressed if the hybrids also carry Dsim\Hmr+t8.6 or Dmau\Hmr+t9.4.

Hmr1 suppresses hybrid male lethality of hybrid sons of crosses between D.melanogaster females and D.mauritiana males. This hybrid rescue is not suppressed if the hybrids also carry Dsim\Hmr+t8.6 or Dmau\Hmr+t9.4.

The sterility of hybrid daughters of crosses between D.melanogaster females and D.simulans males is suppressed by Hmr2. This Hmr2-dependent rescue of hybrid female sterility is not affected if the hybrids also carry Dsim\Hmr+t8.6.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

In(1)AB suppresses hybrid male lethality of hybrid sons of crosses between D.melanogaster females and D.simulans males. This hybrid rescue is not suppressed if the hybrids also carry Dsim\Hmr+t8.6 or Dmau\Hmr+t9.4. Hmr1 suppresses hybrid male lethality of hybrid sons of crosses between D.melanogaster females and D.mauritiana males. This hybrid rescue is not suppressed if the hybrids also carry Dsim\Hmr+t8.6 or Dmau\Hmr+t9.4. The sterility of hybrid daughters of crosses between D.melanogaster females and D.simulans males is suppressed by In(1)AB. This In(1)AB-dependent rescue of hybrid female sterility is not affected if the hybrids also carry Dsim\Hmr+t8.6.

Xenogenetic Interactions
Statement
Reference

The reduced viability of HmrDf/HmrDf females that is seen at 27[o]C is not rescued by Dsim\Hmr+t8.6, while the reduced fertility phenotype of HmrDf/HmrDf females is partially complemented by Dsim\Hmr+t8.6.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Dsim\Hmr+t8.6
Name Synonyms
Secondary FlyBase IDs
    References (3)