FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Dic61Bc05439
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General Information
Symbol
Dmel\Dic61Bc05439
Species
D. melanogaster
Name
FlyBase ID
FBal0185082
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous Dic61Bc05439 mutants show developmental delay and eclose 24 to 36 hours later than wild type. This phenotype is seen at both 22[o]C and 25[o]C. No defects are seen in the tergites or sternites.

Dic61Bc05439 mutants exhibit pupal lethality when raised at 29[o]C. Approximately 20% of homozygotes and 55% of heterozygotes eclose as flies.

Dic61Bc05439 mutant testes are packed with abnormally bent sperm bundles, making the testes bulge slightly in the middle region and displacing all other cell types from their orderly arrangement. The individualisation complexes are well-organised, but actin cones appear disrupted soon after commencing the journey towards the caudal end of sperm tails and degrade prematurely in the middle region of the testis, before the sperm are individualised.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments

Dic61Bc05439 fails to complement the male sterile phenotype seen in Dic61Bms21.

Dic61Bc05439 fails to complement the male sterile phenotype seen in either Df(3L)ED201 or Df(3L)Exel6083.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Precise excision of the PBac{PB} transposon in PBac{PB}Dic61Bc05439 rescues the male sterility.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG7051c05439
Dic61Bc05439
Name Synonyms
Secondary FlyBase IDs
    References (2)