FlyBase Allele Report: Dmel\Archease[c01013]

General Information

Symbol

Dmel\Archease^c01013

Species

D. melanogaster

Name

FlyBase ID

FBal0185238

Feature type

allele

Associated gene

Dmel\Archease

Associated Insertion(s)

PBac{PB}Archease^c01013

Carried in Construct

Also Known As

Archease^PBc01013

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - genetic evidence

amorphic allele - molecular evidence

Mutagen

piggyBac activity

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Song et al., 2015)

amorphic allele - molecular evidence

(Song et al., 2015)

Mutagen

piggyBac activity

(Gene Disruption Project members and Exelixis, 2005)

Progenitor genotype

Associated Insertion(s)

PBac{PB}Archease^c01013

Cytology

Description

Insertion in the 5'UTR which eliminates the production of Archease transcripts.

(Song et al., 2015)

Allele components

Component

Use(s)

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:21,662,886..21,662,886 [+]

(Wang et al., 2025, Song et al., 2015, Gene Disruption Project members and Exelixis, 2005)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell growth rate | second instar larval stage | conditional

(Song et al., 2015)

decreased cell growth rate | second instar larval stage | conditional (with Df(3R)BSC678)

(Song et al., 2015)

decreased cell growth rate | second instar larval stage | conditional (with Df(3R)ED6076)

(Song et al., 2015)

lethal - all die before end of larval stage

(Song et al., 2015)

Phenotype Manifest In

Detailed Description

Statement

Reference

Axon regeneration is significantly impaired in Archease^c01013/Archease^c01013, Archease^c01013/Df(3R)ED6076 or Archease^c01013/Df(3R)BSC678 larvae compared to wild type.

(Song et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Archease^c01013 is a suppressor of increased cell growth rate | second instar larval stage | conditional phenotype of Rtca^NP5057

(Song et al., 2015)

Other

Statement

Reference

Archease^c01013, RtcB^1-4B has abnormal neuroanatomy | larval stage phenotype

(Wang et al., 2025)

Archease^c01013, RtcB^1-4B has abnormal wound healing | larval stage phenotype

(Wang et al., 2025)

Phenotype Manifest In

Other

Statement

Reference

Archease^c01013, RtcB^1-4B has axon | larval stage phenotype

(Wang et al., 2025)

Archease^c01013, RtcB^1-4B has larval dorsal multidendritic neuron ddaC phenotype

(Wang et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Enhanced axon regeneration seen in Rtca^NP5057/Rtca^NP5057 larvae is abolished in Rtca^NP5057;Archease^c01013 double mutants.

(Song et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

85346

w¹¹¹⁸; PBac{PB}Archease^c01013/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Archease^PB

(Wang et al., 2025)

Archease^PBc01013

(Wang et al., 2025, Song et al., 2015)

Archease^c01013

CG6353^c01013

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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