FlyBase Allele Report: Dmel\hec[f06077]

General Information

Symbol

Dmel\hec^f06077

Species

D. melanogaster

Name

FlyBase ID

FBal0185625

Feature type

allele

Associated gene

Dmel\hec

Associated Insertion(s)

PBac{WH}hec^f06077

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

piggyBac activity

Nature of the Allele

Allele class

Mutagen

piggyBac activity

(Gene Disruption Project members and Exelixis, 2005)

Progenitor genotype

Associated Insertion(s)

PBac{WH}hec^f06077

Cytology

Description

Allele components

Component

Use(s)

Inserted element

PBac{WH}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:12,951,727..12,951,727 [-]

(Gene Disruption Project members and Exelixis, 2005)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal mating behavior | male limited

(Li et al., 2011)

Phenotype Manifest In

Detailed Description

Statement

Reference

There is a significant drop in the courtship index (CI, the fraction of time spent performing any of the steps of courtship) of mutant males. They are capable of all courtship steps, but perform them less frequently. Short-term locomotor activity is unaffected. The male courtship phenotype is still observed if mutants are deprived of visual input or paired with young/mature virgin females. Mutant males do not show increased male-male courtship.

hec^f06077 male flies missing the third antennal segment show significantly reduced courtship compared to control males under red light.

(Li et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

hec^f06077 has abnormal mating behavior | male limited phenotype, enhanceable by fru[+]/fru⁴

(Li et al., 2011)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

When hec^f06077 is placed in a fru⁴/+ background, a significantly lower courtship index is observed in males than in the hec^f06077 males alone.

(Li et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

hec^f06077 is rescued by hec^UAS.cLa/Scer\GAL4^hec.PL

(Li et al., 2011)

hec^f06077 is rescued by Scer\GAL4^fru.P1.D/hec^UAS.cLa

(Li et al., 2011)

Comments

Expression of hec^Scer\UAS.cLa using Scer\GAL4^hec.PL or Scer\GAL4^fru.P1.D completely rescues the courtship phenotype of hec^f06077 males.

Expression of hec^Scer\UAS.cLa only in adult mature males using Scer\GAL4^hec.PL or Scer\GAL4^fru.P1.D together with the Scer\GAL80^ts.αTub84B system completely rescues the courtship phenotype of hec^f06077 males.

(Li et al., 2011)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

85712

w¹¹¹⁸ PBac{WH}hec^f06077

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG4395^f06077

(Li et al., 2011)

PBac4395^f06077

(Li et al., 2011)

PBacCG4395^f06077

(Li et al., 2011)

hec^f06077

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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