FB2026_02 , released June 18, 2026
Allele: Dmel\Or22aUAS.cLb
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General Information
Symbol
Dmel\Or22aUAS.cLb
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct b of Larsson
FlyBase ID
FBal0189701
Feature type
allele
Associated gene
Dmel\Or22a
Associated Insertion(s)
Carried in Construct
P{UAS-Or22a.L}
Key Links
Transgenic product class
wild_type
(Larsson et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Larsson et al., 2004)
Mutagen
in vitro construct
(Larsson et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Or22a.L}
Cytology
Description

UASt sequences drive expression of full-length Or22a.

(Larsson et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Or22a
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ectopic expression of Or22aScer\UAS.cLb under the control of Scer\GAL4Or67d.PF in olfactory sensory neurons that normally express Or67b confers a response to a panel of known Or22a ligands (ethyl butyrate, methyl butyrate, pentyl acetate, methyl hexanoate and methyl octanoate) in addition to the endogenous response of these neurons to cis-vaccenyl acetate (cVA), but not to a control odour, geranyl acetate.

      (Benton et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Olfactory sensory neurons expressing Or22aScer\UAS.cLb under the control of Scer\GAL4Or67d.PF still show the ectopic responses to a panel of known Or22a ligands (ethyl butyrate, methyl butyrate, pentyl acetate, methyl hexanoate and methyl octanoate) in a Snmp1/Snmp2 background, but the endogenous response of these neurons to cis-vaccenyl acetate is lost in the Snmp1/Snmp2 background.

      (Benton et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Or22aScer\UAS.cLb
      Or22aUAS.cLb
      Name Synonyms
      Saccharomyces cerevisiae UAS construct b of Larsson
      (Larsson et al., 2004)
      Secondary FlyBase IDs
        References (3)