FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\RUNX1UAS.cMb
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General Information
Symbol
Hsap\RUNX1UAS.cMb
Species
H. sapiens
Name
Saccharomyces cerevisiae UAS construct b of Mathey-Prevot
FlyBase ID
FBal0190195
Feature type
allele
Associated gene
Hsap\RUNX1
Associated Insertion(s)
Carried in Construct
P{UAS-Hsap\RUNX1.M}
Key Links
Transgenic product class
wild_type
(Wildonger and Mann, 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wildonger and Mann, 2005)
Mutagen
in vitro construct
(Wildonger and Mann, 2005)
Progenitor genotype
Carried in construct
P{UAS-Hsap\RUNX1.M}
Cytology
Description

UAS sequences drive expression of Hsap\RUNX1.

(Wildonger and Mann, 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\RUNX1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Hsap\RUNX1Scer\UAS.cMb under the control of Scer\GAL4lz-gal4 results in eyes that appear glazed, due to the fact that individual ommatidia are virtually impossible to discern. Expression of this transgene under the control of Scer\GAL4GMR.PF results in eyes that are reduced in size. In the posterior of eye discs expressing Hsap\RUNX1Scer\UAS.cMb under the control of Scer\GAL4GMR.PF, the ommatidial clusters appear to degenerate.

      (Wildonger and Mann, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      B. Mathey-Prevot

      (Wildonger and Mann, 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\RUNX1Scer\UAS.cMb
      Hsap\RUNX1UAS.cMb
      Name Synonyms
      Saccharomyces cerevisiae UAS construct b of Mathey-Prevot
      (Wildonger and Mann, 2005)
      Secondary FlyBase IDs
        References (1)