FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\borrunspecified
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General Information
Symbol
Dmel\borrunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0190272
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    The number of mitotic cells per hemi-neuromere in Borrunspecified mutant embryos is reduced significantly to approximately 50% of the wild-type at stage 12, and to approximately 20% of the wild-type at stage 14. In addition, the overall number of cells per hemi-neuromere is also lower than normal in Borrunspecified cells. The percentages of prophase and prometaphase cells are higher in Borrunspecified mutants compared with the wild-type, whereas anaphases and telophases are underrepresented in the mutants. This profile shift of the mitotic stages appears to be progressive during embryonic development, and becomes more pronounced by stage 14 when telophases have become exceedingly rare, maybe as a result of cumulative defects during consecutive abnormal cell divisions. Many of the rare anaphases detected at stage 12 appear to be abnormal, exhibiting uneven segregation of chromatin.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Borrunspecified
    borrunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (2)