FB2026_02 , released June 18, 2026
Allele: Dmel\fzΔCRD1.αTub84B
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General Information
Symbol
Dmel\fzΔCRD1.αTub84B
Species
D. melanogaster
Name
FlyBase ID
FBal0190690
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

A αTub84B promoter drives expression of fz from which the entire amino-terminal cysteine-rich domain has been removed.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of one copy of the fz57.αTub84B transgene partially rescues the cuticle phenotype of fzGL31, fz2e2 embryos. However, denticles are present in regions that should be entirely naked and some denticle belts are fused. The mutant lethality is not rescued. fzGL31, fz2e2 clones in the wing that are rescued by fzΔCRD1.αTub84B have ectopic margin bristles, but these appear to be derived from neighbouring cells as the bristles are dark, while the clones lack y.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
fzΔCRD1.αTub84B
Name Synonyms
Secondary FlyBase IDs
    References (1)