FB2026_02 , released June 18, 2026
Allele: Dmel\GαiG204A.UAS
Open Close
General Information
Symbol
Dmel\GαiG204A.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0191152
Feature type
allele
Associated gene
Dmel\Gαi
Associated Insertion(s)
Carried in Construct
P{UAS-Gαi.G204A}
Key Links
Transgenic product class
missense_variant
(Yu et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Yu et al., 2005)
Mutagen
in vitro construct
(Yu et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Gαi.G204A}
Cytology
Description

A mutated Gαi cDNA (carries the amino acid replacement G204A) is cloned downstream of UASt regulatory sequences.

(Yu et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Gαi
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The majority of G-iα65Aunspecified mutant neuroblasts over-expressing the constitutively active G-iα65AG204A.Scer\UAS transgene, under the regulation of Scer\GAL4mat.αTub67C.T:Hsim\VP16 divide to produce two daughter cells of similar size (82%), as oppose to asymmetrically as in wild-type neuroblasts.

      (Yu et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      G-iα65AG204A.Scer\UAS
      GαiG204A.Scer\UAS
      GαiG204A.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)