FB2026_03 , released September 17, 2026
Allele: Dmel\fzWIFCRD.αTub84B
Open Close
General Information
Symbol
Dmel\fzWIFCRD.αTub84B
Species
D. melanogaster
Name
FlyBase ID
FBal0191839
Feature type
allele
Associated gene
Dmel\fz
Associated Insertion(s)
Carried in Construct
P{αTub84B-fz.WIFCRD}
Key Links
Transgenic product class
missense_variant
(Povelones and Nusse, 2005)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Povelones and Nusse, 2005)
Mutagen
in vitro construct
(Povelones and Nusse, 2005)
Progenitor genotype
Carried in construct
P{αTub84B-fz.WIFCRD}
Cytology
Description

A αTub84B promoter drives expression of fz, which has the Wnt inhibitory factor (WIF) domain of Hsap\WIF1 in place of the fz cysteine-rich domain.

(Povelones and Nusse, 2005)
Allele components
Component
Use(s)
Regulatory region(s)
αTub84B
Encoded product / tool
fz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      fzGL31, fz2e2 clones rescued by fzWIFCRD.αTub84B still show observable defects in the patterning of the margin, with some places where a bristle socket has formed in the place of an apparently missing bristle.

      (Povelones and Nusse, 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fzWIF
      (Povelones and Nusse, 2005)
      fzWIFCRD.αTub84B
      Name Synonyms
      Secondary FlyBase IDs
        References (1)