FB2026_02 , released June 18, 2026
Allele: Dmel\Polr3DEY22749
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General Information
Symbol
Dmel\Polr3DEY22749
Species
D. melanogaster
Name
FlyBase ID
FBal0192697
Feature type
allele
Associated gene
Dmel\Polr3D
Associated Insertion(s)
P{EPgy2}Polr3DEY22749
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Bellen, 2006.8.3)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}Polr3DEY22749
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      RpIIIC53EY22749 is homozygous lethal but heterozygous females are significantly long lived compared to controls.

      (Filer et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (7)
      Reported As
      Symbol Synonym
      CG5147EY22749
      (Filer et al., 2017, Bellen, 2006.8.3)
      Polr3DEY22749
      (Ureña et al., 2024)
      Polr3DΔ
      (Ureña et al., 2024)
      RpIIIC53EY22749
      Rpc53EY22749
      dC53EY22749
      (Filer et al., 2017)
      dC53EY
      (Filer et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)