FlyBase Allele Report: Dmel\insv[23I]

General Information

Symbol

Dmel\insv^23I

Species

D. melanogaster

Name

FlyBase ID

FBal0193100

Feature type

allele

Associated gene

Dmel\insv

Associated Insertion(s)

Carried in Construct

Also Known As

insv^23L

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Reeves and Posakony, 2005)

Progenitor genotype

P{SUPor-P}KG07404

(Reeves and Posakony, 2005)

Cytology

Description

excision of P{SUPor-P}KG07404 has deleted sequence from the P{SUPor-P}KG07404 insertion site into the insv coding region including all of the first exon and under half of the second.

(Reeves and Posakony, 2005)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Duan et al., 2011)

visible

(Duan et al., 2011)

visible (with insv^23B)

(Duan et al., 2011)

Phenotype Manifest In

adult abdominal sensillum

(Duan et al., 2011)

adult abdominal sensillum (with insv^23B)

(Duan et al., 2011)

tormogen cell | ectopic

(Duan et al., 2011)

tormogen cell | ectopic (with insv^23B)

(Duan et al., 2011)

trichogen cell

(Duan et al., 2011)

trichogen cell (with insv^23B)

(Duan et al., 2011)

Detailed Description

Statement

Reference

Homozygous and insv^23B/insv^23I adults consistently have a small number of double-socketed sensory organs on the abdomen, with the shaft cells having been replaced by socket cells.

(Duan et al., 2011)

FlyBase curator comment: The strong sensory organ defects reported in FBrf0183881 for insv^23I mutant clones have subsequently been shown to be due to a second-site mutation in l(2)gl that is also present on the mutant chromosome (see FBrf0207678).

(Reeves and Posakony, 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

The stock contains a second-site deletion uncovering l(2)gl (determined using complementation and PCR tests).

(Roegiers et al., 2009)

The insv^23I mutant chromosome has been cleaned up to remove the second-site mutation in l(2)gl which was shown in FBrf0183881 to be present on the chromosome.

(Duan et al., 2011)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

23I

(Reeves and Posakony, 2005)

CG3227^23I

insv^23I

insv^23L

(Duan et al., 2011, Roegiers et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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