FB2026_03 , released September 17, 2026
Allele: Dmel\e(r)T18A.S24A
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General Information
Symbol
Dmel\e(r)T18A.S24A
Species
D. melanogaster
Name
FlyBase ID
FBal0193297
Feature type
allele
Associated gene
Dmel\e(r)
Associated Insertion(s)
Carried in Construct
P{e(r)T18A.S24A}
Key Links
Transgenic product class
missense_variant
(Gelsthorpe et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Gelsthorpe et al., 2006)
Mutagen
in vitro construct
(Gelsthorpe et al., 2006)
Progenitor genotype
Carried in construct
P{e(r)T18A.S24A}
Cytology
Description

A 6.1kb SalI genomic fragment containing the e(r) coding sequence, into which amino acid substitutions T18A and S24A have been introduced.

(Gelsthorpe et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
e(r)
Encoded product / tool
e(r)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      e(r)T18A.S24A fails to rescue e(r)p2

      (Gelsthorpe et al., 2006)

      e(r)T18A.S24A fails to rescue e(r)p1

      (Gelsthorpe et al., 2006)
      Comments

      e(r)T18A.S24A fails to suppress the ability of e(r)p1 to enhance the mutant wing phenotype of rhd1-12.

      e(r)T18A.S24A fails to suppress the synthetic lethality caused by e(r)p2 in combination with Nnd-p.

      (Gelsthorpe et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      e(r)T18A.S24A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)