FlyBase Allele Report: Dmel\path[GS11111]

General Information

Symbol

Dmel\path^GS11111

Species

D. melanogaster

Name

FlyBase ID

FBal0193814

Feature type

allele

Associated gene

Dmel\path

Associated Insertion(s)

P{GSV6}path^GS11111

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Goberdhan et al., 2005)

Progenitor genotype

Associated Insertion(s)

P{GSV6}path^GS11111

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GSV6}

misexpression element

Regulatory region(s)

UASt

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:9,504,827..9,504,827

(Goberdhan et al., 2005)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number, with Scer\GAL4^en-e16E

(Goberdhan et al., 2005)

increased cell size, with Scer\GAL4^en-e16E

(Goberdhan et al., 2005)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Goberdhan et al., 2005)

eye (with path^GS13857), with Scer\GAL4^GMR.PF

(Goberdhan et al., 2005)

ommatidium, with Scer\GAL4^GMR.PF

(Goberdhan et al., 2005)

ommatidium (with path^GS13857), with Scer\GAL4^GMR.PF

(Goberdhan et al., 2005)

wing, with Scer\GAL4^en-e16E

(Goberdhan et al., 2005)

Detailed Description

Statement

Reference

Overexpression of path^GS11111, under the control of Scer\GAL4^GMR.PF, increases both ommatidial and overall eye size.

When path^GS11111 and path^GS13857 are coexpressed under the control of Scer\GAL4^GMR.PF the resulting eyes bulge more from the head capsule and the ommatidial array is mildly disorganised.

path^GS11111 overexpression in the posterior wing compartment of the wing, driven by Scer\GAL4^en-e16E, produces an increase in cell size, even though wing area is reduced.

(Goberdhan et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

203076

y¹ w^67c23; P{GSV6}path^GS11111/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

path^GS11111

(Goberdhan et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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