FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Khc-73UAS.Tag:HA
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General Information
Symbol
Dmel\Khc-73UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0193854
Feature type
allele
Associated gene
Dmel\Khc-73
Associated Insertion(s)
Carried in Construct
P{UAS-Khc-73.HA}
Key Links
Transgenic product class
cDNA
(Siegrist and Doe, 2005)
wild_type
(Siegrist and Doe, 2005)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Siegrist and Doe, 2005)
wild_type
(Siegrist and Doe, 2005)
Mutagen
in vitro construct
(Siegrist and Doe, 2005)
Progenitor genotype
Carried in construct
P{UAS-Khc-73.HA}
Cytology
Description

UASt regulatory sequences drive expression of full-length Khc-73 (corresponds to the two partial yet overlapping ESTs LP11192 and GH09175), which is tagged with Tag:HA.

(Siegrist and Doe, 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Khc-73
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Khc-73Scer\UAS.T:Ivir\HA1 driven by Scer\GAL4BG380 induces a strong increase in quantal content (QC) at larval neuromuscular junctions.

      Overexpression of Khc-73Scer\UAS.T:Ivir\HA1 driven by Scer\GAL4unspecified in motor neurons results in a statistically significant increase in the number of T bars per active zone compared with that for wild-type.

      (Tsurudome et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Khc-73Scer\UAS.T:Ivir\HA1
      Khc-73UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (4)