FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pinta1
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General Information
Symbol
Dmel\pinta1
Species
D. melanogaster
Name
FlyBase ID
FBal0194700
Feature type
allele
Associated gene
Dmel\pinta
Associated Insertion(s)
Carried in Construct
Also Known As
pinta
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Wang and Montell, 2005)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q90term.

(Wang and Montell, 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:22,424,420..22,424,420 [-]
Nucleotide change:

C22424420T

Amino acid change:

Q91term | pinta-PA; Q91term | pinta-PB

Reported amino acid change:

Q90term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Wang and Montell, 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      pinta1 animals exhibit defects in the function of abdominal lateral pentascolopidial chordotonal organ lch5 (in third instar larvae) and Johnston organ (in adults) mechanoreceptors compared to controls.

      (Katana et al., 2019)

      Electroretinograms from pinta1 flies fail to show prolonged depolarization afterpotential (PDA) in response to blue light. This phenotype cannot be rescued by feeding flies on vitamin A-containing media.

      (Wang and Montell, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      NOT Enhancer of
      Statement
      Reference

      pinta1 is a non-enhancer of abnormal neurophysiology | third instar larval stage phenotype of santa-maria1

      (Katana et al., 2019)
      NOT Suppressor of
      Statement
      Reference

      pinta1 is a non-suppressor of abnormal neurophysiology | third instar larval stage phenotype of santa-maria1

      (Katana et al., 2019)
      Other
      Statement
      Reference

      pinta1, santa-maria1 has lethal phenotype

      (Katana et al., 2019)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Selected as: a mutation on the third chromosome that causes defects in the visual response as measured by electroretinogram recordings.

      (Wang and Montell, 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pinta
      (Voolstra et al., 2010, Wang and Montell, 2005)
      pinta1
      (Katana et al., 2019, Crocker et al., 2016, Wang and Montell, 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)